A new dawn for androgens: Novel lessons from 11-oxygenated C19 steroids

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• 作者：Elzette Pretorius^a ; Wiebke Arlt^b ; Karl-Heinz Storbeck^a ; ^{storbeck@sun.ac.za}
• 关键词：Adrenal androgens ; Castration resistant prostate cancer (CRPC) ; Congenital adrenal hyperplasia (CAH) ; Polycystic ovary syndrome (PCOS) ; 11-Ketotestosterone (11KT) ; 11-Ketodihydrotestosterone (11KDHT)
• 刊名：Molecular and Cellular Endocrinology
• 出版年：2017
• 出版时间：5 February 2017
• 年：2017
• 卷：441
• 期：Complete
• 页码：76-85
• 全文大小：832 K
• 卷排序：441

文摘

11OHA4 is the precursor to the potent androgens 11KT and 11KDHT. 11-oxygenated C19 steroids likely play a role in androgen related disease states. 11-oxygenated steroids are potentially useful biomarkers.