Application of next generation sequencing for the detection of human viral pathogens in clinical specimens

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• 作者：Jayme Parker^a ; ^b ; Jack Chen^a ; ^b ; ^{j.chen@alaska.edu} ; ^{jiguo.chen@alaska.gov}
• 关键词：NGS ; next generation sequencing ; CPE ; cytopathic effect ; TAT ; turnaround time
• 刊名：Journal of Clinical Virology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：86
• 期：Complete
• 页码：20-26
• 全文大小：2612 K
• 卷排序：86

文摘

NGS technology is compared to conventional laboratory methods in a public health laboratory. Viral genome coverage and read depth of viral nucleic acids in various types of clinical specimens are reported. The need for acceptability standards for NGS due to the scarcity of pathogenic viral nucleic acids is addressed.