Vitamin D deficiency related to physical capacity during cardiac rehabilitation

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• 作者：Olivier Ucay^a ; ^c ; Marion Pouche^a ; ^c ; Thibaut Guiraud^b ; Florent Besnier^b ; Atul Pathak^b ; ^c ; Marc Labrunee^a ; ^b ; ^c ; ^{labrunee.m@chu-toulouse.fr}
• 关键词：Vitamin D deficiency ; Cardiovascular rehabilitation ; 6-min walking test ; Maximal power
• 刊名：Annals of Physical and Rehabilitation Medicine
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：60
• 期：1
• 页码：2-5
• 全文大小：332 K
• 卷排序：60

文摘

Vitamin D deficiency is a frequent pathology associated with cardiovascular diseases and physical performance.ObjectiveTo study the link between 25-hydroxyvitamin D (25OHD) level and physical performance and gain in physical performance after cardiovascular rehabilitation (CVR) with vitamin D deficiency.Methods25OHD level was assessed in a retrospective cohort of patients admitted for CVR. Data were collected on physical fitness [6-min walk test distance (6MWD) in percentage of predicted, maximal power (Pmax)]. The threshold of vitamin D deficiency was 20 ng/ml chosen according to the literature.ResultsAmong the 131 patients included, as compared with those with nondeficiency (n = 83; 63%), patients with vitamin D deficiency (n = 48, 37%) had lower initial 6MWD (82 ± 18 vs 89 ± 12% predicted, P = 0.009) and Pmax (100 ± 58 vs 120 ± 39 W, P = 0.006). After CVR, this difference was maintained. The improvement in 6MWD and Pmax was significantly lower with deficiency than nondeficiency, for an increase of 11 ± 8% versus 14 ± 9% predicted (P = 0.048) and 10 ± 30 versus 32 ± 30 W (P = 0.00001), respectively.ConclusionVitamin D deficiency may be associated with impaired physical fitness before CVR and a smaller gain in physical fitness with CVR, probably related to the action of vitamin D on the muscle.