Low vitamin D does not predict statin associated muscle symptoms but is associated with transient increases in muscle damage and pain

详细信息    查看全文

• 作者：Beth A. Taylor^a ; ^b ; ^c ; ^{Beth.Taylor@uconn.edu} ; Lindsay Lorson^b ; C. Michael White^c ; Paul D. Thompson^b ; ^c
• 关键词：Statin myalgia ; Muscle symptoms ; Vitamin D deficiency
• 刊名：Atherosclerosis
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：256
• 期：Complete
• 页码：100-104
• 全文大小：564 K
• 卷排序：256

文摘

We assessed associations between Vitamin D and development of statin-associated muscle symptoms (SAMS). Baseline Vitamin D and changes in Vitamin D with simvastatin did not predict SAMS. Clinical Vitamin D deficiency and insufficiency did not predict SAMS. Low Vitamin D was associated with transient increases in creatine kinase and pain. Future studies are needed to clarify the relationship between Vitamin D and SAMS.