Vitamin E deficiency depressed fish growth, disease resistance, and the immunity and structural integrity of immune organs in grass carp (Ctenopharyngodon idella): Referring to NF-κB, TOR and Nrf2 signaling

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• 作者：Jia-Hong Pan^a ; ¹ ; Lin Feng^a ; ^b ; ^c ; ¹ ; Wei-Dan Jiang^a ; ^b ; ^c ; Pei Wu^a ; ^b ; ^c ; Sheng-Yao Kuang^d ; Ling Tang^d ; Yong-An Zhang^e ; Xiao-Qiu Zhou^a ; ^b ; ^c ; ^{xqzhouqq@tom.com} ; ^{zhouxq@sicau.edu.cn} ; Yang Liu^a ; ^b ; ^c ; ^{kyckgk@hotmail.com}
• 关键词：Vitamin E ; Grass carp (Ctenopharyngodon idella) ; Immunity ; Antioxidant capacity ; Apoptosis ; Immune organs
• 刊名：Fish & Shellfish Immunology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：60
• 期：Complete
• 页码：219-236
• 全文大小：4462 K
• 卷排序：60

文摘

Vitamin E deficiency depressed the immunity of head kidney, spleen and skin. Vitamin E deficiency aggravated the inflammatory response. Vitamin E deficiency decreased head kidney, spleen and skin antioxidant capacity. Vitamin E deficiency induced head kidney, spleen and skin apoptosis. Vitamin E regulated signaling molecules NF-κB, TOR and Nrf2 mRNA expression.