Preliminary study of the relationship between DAZ gene copy deletions and spermatogenic impairment in Chinese men

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• 作者：Yuan Yang ; Cuiying Xiao ; Sizhong Zhang ; A. Zhoucun ; Xiang Li ; Sixiao Zhang
• 刊名：Fertility and Sterility
• 出版年：2006
• 出版时间：April 2006
• 年：2006
• 卷：85
• 期：4
• 页码：1061-1063
• 全文大小：79 K

文摘

Copy deletion screening of DAZ gene family on the Y chromosome in 485 patients with idiopathic azoospermia or oligozoospermia and 236 fertile men revealed that the prevalence of deletion patterns of the entire DAZ gene and DAZ1/DAZ2 gene were significantly higher in the patients than in fertile men. The deletion patterns correlate with spermatogenic impairment in a Chinese population.