Effect of DSP4 and desipramine in the sensorial and affective component of neuropathic pain in rats
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- 作者：Lidia Bravoa ; b ; c ; Juan A. Micoa ; b ; d ; Raquel Rey-Breaa ; Carmen Camarena-Delgadoa ; Esther Berrocosoa ; b ; c ; esther.berrocoso@uca.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：Acetone (PubChem CID ; 180) ; Chloral hydrate (PubChem CID ; 270) ; Desipramine (PubChem CID ; 2995) ; DSP4 ; [N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride] (PubChem CID ; 3172) ; Ketamine Hydrochloride (PubChem CID ; 15851) ; Sodium chloride (PubChem CID ; 5234) ; Xylazine ; (PubChem CID ; 5707)
- 刊名：Progress in Neuropsychopharmacology & Biological Psychiatry
- 出版年：2016
- 出版时间：3 October 2016
- 年：2016
- 卷：70
- 期：Complete
- 页码：57-67
- 全文大小：1502 K
文摘
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DSP4 did not modify sensorial pain responses in neuropathic animals.
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DSP4 accentuated neuropathic escape behavior in the place escape/avoidance test.
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DSP4 enhanced ERK activation in the anterior cingulate cortex in neuropathic animals.
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20">Desipramine attenuated the place escape/avoidance behavior in neuropathic animals.
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25">Desipramine did not modify p-ERK expression in the anterior cingulate cortex.
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