Developmental DSP4 effects on cortical Arc expression
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- 作者：Jeff Sanders ; jeff.d.sanders@emory.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Arc ; activity regulated cytoskeleton associated protein ; IEG ; immediate early gene ; LTP ; long term potentiation ; PBS ; phosphate-buffered saline ; DSP4 ; N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride ; PND ; postnatal day ; NET ; norepinephrine transporter
- 刊名：Neuroscience Letters
- 出版年：2016
- 出版时间：8 April 2016
- 年：2016
- 卷：618
- 期：Complete
- 页码：89-93
- 全文大小：1069 K
文摘
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Arc mRNA is differentially regulated by norepinephrine at different ages.
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There is an absence of Arc mRNA response to DSP4 in preadolescence.
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There is a changing Arc mRNA response to DSP4 in adolescence.
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20">Mature noradrenergic regulation of Arc mRNA is not intact until late adolescence.
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25">Arc mRNA decreases in DSP4 lesioned adult rats.