Comparative toxicity, oxidative stress and endocrine disruption potential of plasticizers in JEG-3 human placental cells

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• 作者：Elisabet Pé ; rez-Albaladejo ; ^{ealqam@cid.csic.es} ; Denise Fernandes ; Silvia Lacorte ; Cinta Porte ; ^{cinta.porte@cid.csic.es}
• 关键词：P450 aromatase ; ROS generation ; JEG-3 cells ; Bioavailability ; Plasticizers
• 刊名：Toxicology in Vitro
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：38
• 期：Complete
• 页码：41-48
• 全文大小：659 K
• 卷排序：38

文摘

Alkylphenols increased P450 aromatase activity in human placental cells JEG-3. The low bioavailability masked the endocrine disrupting potential of BBP and DBP. NP, OP and BPA generated reactive oxygen species in JEG-3 cells.