Gonadotropin-releasing hormone agonist with or without raloxifene: Effects on cognition, mood, and quality of life
文摘
GnRH analogue (GnRH-a) administration induces a significant reduction of cognitive functions in premenopausal women with symptomatic uterine leiomyomas and, notwithstanding the appearance of climacteric-like symptoms, the effectiveness of analogue induces a significant improvement of mood and quality of life. The addition of raloxifene to GnRH-a treatment has no clinical effect on cognition, mood, and quality of life in this sample of women.