Physiological functions of Vitamin D in adipose tissue

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• 作者：Manal A. Abbas ^{manabbas@yahoo.com}
• 关键词：VDR ; Adipose tissue ; Adipogenesis ; Adipokines ; Obesity
• 刊名：The Journal of Steroid Biochemistry and Molecular Biology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：165
• 期：part_PB
• 页码：369-381
• 全文大小：1507 K
• 卷排序：165

文摘

​​​​​​​Vitamin D metabolizing enzymes and VDR are expressed in adipose tissue. Vitamin D regulates adipogenesis and adipocyte apoptosis. Through its genomic action, vitamin D regulates energy metabolism by controlling the expression of uncoupling proteins and the appetite suppressing hormone leptin. MmVDR is present in caveolae of the plasma membrane and is the same as the classic nVDR. Vitamin D reduces adipose tissue inflammation. Obesity is associated with vitamin D deficiency but vitamin D deficiency does not predispose to obesity.