Low-intensity pulsed ultrasound upregulates pro-myelination indicators of Schwann cells enhanced by co-culture with adipose-derived stem cells

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• 作者：Yuan Yue ; Xingmei Yang ; Liang Zhang ; Xun Xiao ; Neel R. Nabar ; Yunfeng Lin ; Liang Hao ; Dongjiao Zhang ; Jingyi Huo ; Jingle Li ; Xiaoxiao Cai and Min Wang
• 刊名：Cell Proliferation
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：49
• 期：6
• 页码：720-728
• 全文大小：908K
• ISSN：1365-2184

文摘

Peripheral nerve injuries are a common occurrence, resulting in considerable patient suffering; it also represents a major economic burden on society. To improve treatment options following peripheral nerve injuries, scientists aim to find a way to promote Schwann cell (SC) myelination to help nerves to carry out their functions effectively. In this study, we investigated myelination ability of SCs, regulated by co-culture with adipose-derived stem cells (ASCs) or low-intensity pulsed ultrasound (LIPUS), and synergistic effects of combined treatments.