The adhesion of herbicide droplets on leaf surfaces plays an important role in the herbicide's adsorption by crops. How to control the adhesive binding which occurs through dynamic self-assembly between the macroscopic droplet and the surface is a challenging task. We introduce a host onto surfaces that controls the binding of guests in the paraquat droplets. The pillar[5]arene-functional surface showed the selective binding of paraquat droplets via the host–guest interaction. The work is promising for improving the efficiency of herbicides.