Synbiotics suppress the release of lactate dehydrogenase, promote non-specific immunity and integrity of jejunum mucosa in piglets

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• 作者：Zuzana Andrejč&#225 ; kov&#225 ; Drahomí ; ra Sopkov&#225 ; Radoslava Vlčkov&#225 ; Lucia Kulichov&#225 ; Soňa Gancarčí ; kov&#225 ; Viera Alm&#225 ; šiov&#225 ; Katarí ; na Holovsk&#225 ; Vladimí ; r Petrilla and Lenka Kreš&#225 ; kov&#225
• 刊名：Animal Science Journal
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：87
• 期：9
• 页码：1157-1166
• 全文大小：492K
• ISSN：1740-0929

文摘

The aim of our experiment was to study how synbiotics are able to deal with the problems of post-weaning piglets. Lactobacillus plantarum – Biocenol^TM LP96 (CCM 7512), Lactobacillus fermentum – Biocenol^TM LF99 (CCM 7514) and flaxseed (rich in n-3 polyunsaturated fatty acids) were administered to 36 conventional piglets from a problematic breed with confirmed presence of enterotoxigenic Escherichia coli and Coronavirus. The experimental piglets were supplied with probiotic cheeses and crushed flax-seed in the period starting 10 days before weaning and lasting up to 14 days post-weaning. Piglets in the control group were supplied only control cheese. The impact of such additives on the release of lactate dehydrogenase (LDH; spectroscopic and electrophoretic assay), alteration of immunity (index of metabolic activity), jejunum histology (light microscopy), and health of conventional piglets from a problematic breed (monitoring of hematology, consistency and moisture of feces and body temperature) were examined. We found significant decrease in LDH leakage in the blood serum and tissue extracts, indicating better cell membrane integrity in the individual organs of animals. Probiotics and flaxseed applied together seem to be a good source of nutrients to improve the immune status and the integrity of jejunum mucosa during infection.