Based on the high-quality seismic profiles acquired from the northern South China Sea(SCS), we performed a detailed seismic sequence stratigraphic study. Correlation of the results with core samples and logging data from ODP Leg 184 and other deep sea records have been carried out to detect the difference and connection between geological and geophysical research methods, so as to reconstruct the sedimentary history of this area. Detailed analyses of their reflecting characters, top and bottom ages, thickness and sedimentary rate helped build a Quaternary seismic stratigraphic framework at a resolution of ~10 ka. Consistency between seismic profiles and drilling data of ODP Sites 1144 and 1146 indicates that high resolution seismic analyses can produce a direct, detailed and reliable stratigraphic division scheme better than the traditional petrographic description sometimes.