The tectonic setting of the Cambrian siliceous rocks in the Zhejiang-Guangxi-Guizhou zone are discussed with the aid of major and rare earth element geochemistry. The results show that the Cambrian siliceous rocks in the Zhejiang-Guangxi-Guizhou zone were formed in the continental-margin environment or transitional zone from the continental margin to deep sea. LREEs are more enriched in the siliceous rocks from early rift basins than those from the ancient Huanan residual oceanic basin and Yangtze block. The siliceous rocks formed during tectonic extension tend to have hydrothermal origin, and display the REE distribution patterns of being depleted in LREE and positive Eu anomaly.