Ultrasonic velocity measurements on the schists, gneisses, migmatites, amphibolites and mylonites from Higher Himalayan Crystallines (HHC) and Honghe strike-slip fault zone in the southwestern China show that the average anisotropic magnitude of them is much less than that observed by a series of measurements of surface-wave dispersion inversions and waveform inversions of P to S conversions in these regions. Modeled results indicate that seismic anisotropy can be enhanced by alignment of melt. Geophysical investigations demonstrate that Tibetan and Sichuan-Yunnan crust is characterized by high geothermal gradients and abnormal thickness. The authors attribute the extremely high anisotropy observed within Tibetan and Sichuan-Yunnan crust to aligned melt pocket induced by localized deformation.