Nalati magmatic belt of Late Silurian granites are mainly distributed in north of Nalati-Hongliuhe suture zone, the active continental margin of the southern margin of Kazakhstan Plate. On the basis of geochemical characteristics, the results show that the sequence of granite mixed source in the neutral-acidic quartz diorite-granodiorite composition, belongs to the calc-alkaline series. Chondrite-normalized REE patterns are LREE slightly richer, with LREE/HREE 2.865~5.915, (La/Yb)N 7.23~7.29, δEu 0.52~0.94, and δCe 0.87~0.92, REE and trace elements show the crust-mantle mixed source characteristics of the volcanic arc tectonic setting, and it belongs to volcanic arc granite.