The Dongmozhazhua ore deposit is a new large-size lead-zinc deposit in the south of oft-com:office:smarttags" />Qinghai Province. Based on a considerable number of polished ore sections as well as massive spectrum and electron micro- probe analyses, the systematic study on ore minerals is finished. The results show that the ore mineral is intermediate-temperature hydrothermal mineral association. Wall rock alteration is intermediate-temperature alteration. Sulfide isotope has the characteristic of the sulfides isotope in massive sulfide deposit. Therefore, the Dongmozhazhua lead-zinc deposit has characteristics of the multi-stage and superimposed metallization.oft-com:office:office" />