It is chronically debated on the Permian tectonic evolution of the northern Qiangtang block, oft-com:office:smarttags" />Qinghai—Tibetan Plateau. Newly identification of the Late Permian quartz syenitic porphyries in the Tuotuo River area may provide some constraints on the Paleo-Tethyan tectonic evolution of the northern Qiangtang, even of the whole northern Qinghai—Tibetan Plateau. During the ascending and intrusion, fractional crystallization and crustal contamination may have modified the rock’s chemistry. Obviously, there must be a subduction of oceanic slab during the Late Permian along one margin of the northern Qiangtang block.oft-com:office:office" />