The authors calculate the focal mechanisms of 14 earthquakes with M≥3.0 of the 2000 Yao’an MS6.5 earthquake sequence using the first motions of P, SV and SH waves and their amplitude ratios. The main seismogenic fault of the Yao’an earthquake trends in NW and has high dip angle, showing the feature of right lateral strike-slip under nearly horizontal main pressure stress. The focal faults of the Yao’an earthquake sequence mainly move by strike-slip with sporadic oblique-slip faulting under horizontal or nearly horizontal main pressure stress, and in 1-3 days after the mainshock, the fault slips by the way above mentioned, but in 3-30 days after the mainshock by the way of strike-slip.