///The Cu-Fe-polymetallic metallogenic belt in Nixiong of Tibet is an important part of Gangdise Cu-Fe-polymetallic metallogenic belt. Based on the metallogenic regularity of typical deposits, this paper applied five features of remote sensing technique method for mineral-prospecting and deinterfered anomalous principal component thresholding technique to obtain geological information by ETM+ data, and discussed remote sensing prospecting models suitable for Nixiong metallogenic belt. Through the theory of mathematical statistics, theory of geological anomaly and GIS technique, this study quantitatively analyzed the data from geophysical, remote sensing and delineated prospecting areas. The results reveal that it is efficient and accurate for mineral-prospecting by means of remote sensing combined with basic geological, geophysical and geochemical information, and the method of multi-features remote sensing mineral-prospecting is reliability.