The Wulanwuzhuer deposit is located in the southwest margin of Qaidam Basin. A comprehensive geochemical anomaly has been found by 1∶200 000 geochemical surveys in this area. Through 1∶50 000 stream sediment surveys, the comprehensive geochemical anomaly has been broken down into several secondary anomalies. The Wulanwuzhuer deposit has been found by using rock geochemical survey and engineering verification for the anomalies. The geochemical survey proves to be effective for prospecting multiple metal deposits in the southwest margin of Qaidam Basin.