Through the study and analysis on the seismic tomographic data in the northeastern margin area of Tibetan Plateau, the methodology of crustal 3D database based on MultiPatch format in ArcGIS and the crustal solid structure model of the northeastern margin of Tibetan Plateau with the modern 3D modeling software and technology are presented. It emphasizes the 3D Geosciences modeling theory, the storage methodology of seismic tomographic data and the main technology of 3D solid model. Then, the main methodology is summarized from the fundamental seismic tomographic data to 3D crustal structure model of the northeastern margin of Tibetan Plateau.