The study of Deneng copper-polymetallic deposit in Coqen County, Tibet, shows that in the mineral district there are six ore bodies copper ore with productiongrade of Cu, associated useful components of Pb, Zn, Au, Ag, etc.and good ore-forming geological conditions. The ore bodies are mainly occured in the exocontact zones of Yanshanian guarts diorite porphyrite intrusions and tectonic fracture zones, among them, Cu⁴ ore body is the largest one. The deep drilling and surface trenching show that the variation coefficients of ore grade and thickness along the strike and tendency of ore bodies are small. The quartz diorite porphyrite intrusions of the first time of the first stage late Yanshanian are the main source of ore-forming materials, the late NWW-trending faults are the main ore channels and host structures.