Mesoproterozoic folded basement was unexposed in central Guizhou Province. The thickness and facies of the regional Neoproterozoic sedimentary cover and stratigraphic contact relationship reveal that the Central Guizhou palaeouplift was on the high position of the folded basement before Nanhuaian. South and north margins were still receiving deposits within relative low position of the basement. Neoproterozoic rifting history and geophysical proof also indicate that the basement might have some differences between the palaeouplift area and the marginal area. Thus, the authors could speculate that there has Mesoproterozoic folded basement under the sedimentary cover in correspondence with Sibao Group.