Based on mobile deformation data cross the fault and using grey relation degree analyze method, the authors got the synthetic index for strike-tensile-vertical activity parameters of Xianshuihe Fault. The results showed that: 1) Xianshuihe Fault mainly is left-lateral strike-slip fault; 2) the curve of activity parameters accumulation showed the anomaly variation of speeding up or turning before Xiaojin MS 6.3 and Yajiang MS 6.0 earthquakes; and 3) the authors observed the adjustment influence on the Xianshuihe Fault after the MS 8.1 earthquake at the Western Pass of Kunlun Mountains, stress field intensifying or disturbing influence on Xianshuihe Fault before the Wenchuan MS 8.0 earthquake, and left lateral accelerating influence on Xianshuihe Fault after the Yushu MS 7.1 earthquake in short-time.