The Neogene Zhujiang Formation and Hanjiang Formation of Panyu low uplift in the Zhujiangkou Basin were divided into seven sequences on the basis of an analysis of outcrops, cores, logs, 3-D seismic information and palaeobiologic characteristics. Some were assigned to obvious truncation or obvious overlapping and unconformity, and the others to gentle truncation or overlapping unconformity and conformity. Every thirdorder sequence was divided into system tracts and fourth-order sequences whose boundaries seem to be main flooding surfaces. Combined with the seismic attributes, the distribution and development of the depositional systems in the fourth-order sequences were revealed.