On the basis of 3S and ANN method, by means of RS interpretation, the resources and environment information such as vegetation coverage, exposing rate of rock, relief degree of land surface, the ≥25°slope land area of different land use types is obtained. The results show that the analyses of 3S-ANN are consistent with the actual situation. The warning condition of karst rocky desertification in agricultural land increased constantly from 1977 to 2005. In light of the prediction with the data in 2005 and 2007, it is concluded that the rocky desertification degrees in Dongmiao, Jiagui, Baoan and Daxing townships will aggravate in 2015, so should pay more attention in the prevention and control in future.